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Dentistry · Dental materials and radiology: osteopetrosis
Sample itemA child with pancytopenia and dense bones has a jaw infection after an extraction that does not heal. Which disease is likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Osteopetrosis
Osteopetrosis results from defective osteoclast function causing dense brittle bone, marrow failure and poor blood supply that makes the jaw prone to osteomyelitis. Delayed tooth eruption is common.
Option by option
A. Fibrous dysplasia
Fibrous dysplasia does not cause pancytopenia.
B. Paget disease
Paget disease occurs in older adults.
C. Osteopetrosis (correct)
Correct. Marble bone with marrow failure and osteomyelitis suggests osteopetrosis.
D. Rickets
Rickets causes soft bones, not dense bone.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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