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Dentistry · Dental materials and radiology: Gardner syndrome
Sample itemA young man has multiple osteomas of the jaws, epidermoid cysts of the skin and supernumerary teeth. Which cancer does he need screening for?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Colorectal carcinoma
Gardner syndrome is a variant of familial adenomatous polyposis from APC mutation, with colonic polyps that become malignant without colectomy. Jaw osteomas can be the first sign.
Option by option
A. Oral squamous cell carcinoma
Oral squamous carcinoma is not specifically linked to Gardner syndrome.
B. Basal cell carcinoma
Basal cell carcinomas are the feature of Gorlin syndrome.
C. Thyroid medullary carcinoma
Medullary thyroid carcinoma is a part of MEN 2.
D. Colorectal carcinoma (correct)
Correct. Colonic polyposis carries nearly universal risk of cancer.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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