Nose and paranasal sinuses: leukotriene antagonist: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Nose and paranasal sinuses: leukotriene antagonist

Sample item

A 27-year-old with seasonal allergic rhinitis and asthma still has symptoms despite a steroid spray. Which oral drug acts by blocking cysteinyl leukotriene receptors?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Montelukast

Montelukast antagonises the CysLT1 receptor and is useful in allergic rhinitis, especially with coexisting asthma. It is less effective than intranasal steroids. Its adverse effects include neuropsychiatric symptoms.

Option by option

  • A. Ipratropium

    Ipratropium is an anticholinergic that dries watery rhinorrhoea.

  • B. Pseudoephedrine

    Pseudoephedrine is an oral sympathomimetic decongestant.

  • C. Cetirizine

    Cetirizine is an H1 antihistamine.

  • D. Montelukast (correct)

    Correct. It blocks cysteinyl leukotriene receptors.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this ENT question

What is the answer to this ENT question?

The best answer is D, Montelukast. Montelukast antagonises the CysLT1 receptor and is useful in allergic rhinitis, especially with coexisting asthma.

Why is "Ipratropium" not the answer?

Ipratropium is an anticholinergic that dries watery rhinorrhoea.

Why is "Pseudoephedrine" not the answer?

Pseudoephedrine is an oral sympathomimetic decongestant.

Why is "Cetirizine" not the answer?

Cetirizine is an H1 antihistamine.

What concept does this question test?

It tests Nose and paranasal sinuses: leukotriene antagonist in ENT. It is less effective than intranasal steroids. Its adverse effects include neuropsychiatric symptoms.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nose and paranasal sinuses: leukotriene antagonist?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.