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OBG · Early pregnancy: anembryonic pregnancy
Sample itemA woman with 8 weeks of amenorrhoea has a transvaginal scan showing an empty gestational sac with a mean sac diameter of 26 mm and no yolk sac or embryo. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Anembryonic pregnancy (early pregnancy failure)
A mean sac diameter of 25 mm or more with no embryo diagnoses an anembryonic pregnancy (blighted ovum). Similarly, a crown-rump length of 7 mm or more without cardiac activity indicates failure. These thresholds make the diagnosis safe without waiting.
Option by option
A. Anembryonic pregnancy (early pregnancy failure) (correct)
Correct. A sac of 25 mm or more with no embryo is diagnostic of early pregnancy loss.
B. Ectopic pregnancy with pseudosac
An intrauterine sac of this size is not a pseudosac.
C. Normal pregnancy at 5 weeks; repeat in a week
At 26 mm the sac should already contain an embryo, so waiting is not appropriate.
D. Threatened abortion with good prognosis
The absence of an embryo at this size means the pregnancy is not viable.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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