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OBG · Puerperium: postpartum thyroiditis
Sample itemA woman 3 months postpartum reports palpitations, irritability and weight loss. She has a painless small goitre, a low TSH, raised free T4 and positive anti-TPO antibodies. Radioiodine uptake is low. What is the best initial treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Beta blocker for symptoms, with monitoring for later hypothyroidism
Postpartum thyroiditis is an autoimmune destructive thyroiditis in which a transient thyrotoxic phase at 1 to 4 months is followed by hypothyroidism, then often recovery. Low radioiodine uptake distinguishes it from Graves disease, and antithyroid drugs are not effective as the hormone is leaking, not being overproduced. Beta blockers control symptoms, and thyroxine is given if hypothyroidism develops.
Option by option
A. Carbimazole for 18 months
Antithyroid drugs are ineffective in destructive thyroiditis.
B. Beta blocker for symptoms, with monitoring for later hypothyroidism (correct)
Correct. Symptomatic beta blockade is appropriate, with follow-up for the hypothyroid phase.
C. Radioiodine ablation
Radioiodine would not take up in a thyroid with low uptake and is contraindicated in lactation.
D. Total thyroidectomy
Surgery is unnecessary for a self-limiting condition.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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