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OBG · Gynaecological infections: genital warts
Sample itemA 24-year-old woman at 20 weeks of gestation has multiple vulval warts. Which treatment should be avoided?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Podophyllin or podophyllotoxin
Genital warts are caused by HPV types 6 and 11. Podophyllin, podophyllotoxin and imiquimod are avoided in pregnancy because of potential toxicity and lack of safety data, while trichloroacetic acid, cryotherapy and electrosurgery are acceptable. Caesarean section is not indicated solely for warts unless they obstruct the birth canal.
Option by option
A. Podophyllin or podophyllotoxin (correct)
Correct. Podophyllin-based agents are avoided in pregnancy.
B. Electrocautery
Electrocautery is an accepted option.
C. Cryotherapy
Cryotherapy is acceptable.
D. Trichloroacetic acid application
Trichloroacetic acid is safe in pregnancy.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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