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OBG · Gynaecological endocrinology: LH surge
Sample itemIn a regular 28-day cycle the luteinising hormone surge begins on day 12. When is ovulation expected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. About 34 to 36 hours after the onset of the LH surge
Rising oestradiol from the dominant follicle triggers a positive feedback LH surge, and ovulation occurs about 34 to 36 hours after the onset of the surge and 10 to 12 hours after the LH peak. This timing underlies ovulation predictor kits and timing of hCG trigger and insemination. The surge also initiates luteinisation of the follicle.
Option by option
A. On the day of menstruation
Ovulation occurs mid-cycle and not at menstruation.
B. About 7 days after the surge
A 7-day delay would place ovulation far too late.
C. About 34 to 36 hours after the onset of the LH surge (correct)
Correct. Ovulation follows the surge onset by 34 to 36 hours.
D. Immediately at the start of the surge
Ovulation requires time after the surge for follicle rupture, not immediately.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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