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OBG · Gynaecological endocrinology: acute heavy bleeding
Sample itemA haemodynamically stable 38-year-old with heavy menstrual bleeding for 10 days and normal pelvic ultrasound needs medical control of bleeding. Which oral regimen is commonly used?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Norethisterone 5 mg three times daily
High-dose oral progestins such as norethisterone 5 mg three times daily rapidly stabilise the endometrium and control anovulatory bleeding, and tranexamic acid can be used alongside. The dose is tapered over weeks, and withdrawal bleeding follows stopping. NSAIDs and antifibrinolytics reduce blood loss, but aspirin and anticoagulants worsen it.
Option by option
A. Norethisterone 5 mg three times daily (correct)
Correct. Oral norethisterone is a standard way to arrest acute abnormal uterine bleeding.
B. Aspirin 600 mg four times daily
Aspirin impairs platelet function and increases bleeding.
C. Warfarin
Warfarin would worsen bleeding.
D. Clomiphene 100 mg daily
Clomiphene induces ovulation and is not used to stop bleeding.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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