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OBG · Contraception: antiphospholipid antibodies
Sample itemA 28-year-old with systemic lupus erythematosus and positive antiphospholipid antibodies needs contraception. Which method should be avoided?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Combined oestrogen-containing methods
Positive antiphospholipid antibodies carry a high thrombotic risk, and oestrogen is category 4. Safe options include copper IUCD, levonorgestrel IUS and condoms, and progestogen-only methods other than DMPA are usually preferred in this context. Pregnancy should be planned during quiescent disease.
Option by option
A. Levonorgestrel IUS
The levonorgestrel IUS is safe.
B. Combined oestrogen-containing methods (correct)
Correct. Oestrogen-containing contraceptives raise thrombotic risk with antiphospholipid antibodies.
C. Copper IUCD
A copper IUCD is safe.
D. Condoms
Condoms carry no hormonal risk.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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