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OBG · Gynaecological oncology: vaginal cancer
Sample itemWhich statement about carcinoma of the vagina is correct?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Most vaginal tumours are metastatic or secondary, and primary tumours are usually squamous, treated mainly with radiotherapy
Primary vaginal cancer is rare, accounting for 1 to 2 percent of gynaecological cancers, and most vaginal malignancies are secondary from the cervix, endometrium or vulva. Primary tumours are mostly squamous and HPV-related, with the upper third the commonest site, and treatment is mainly radiotherapy with brachytherapy. Pre-invasive disease is called vaginal intraepithelial neoplasia.
Option by option
A. It is treated by hysterectomy alone
Hysterectomy does not treat a vaginal tumour.
B. Most vaginal tumours are metastatic or secondary, and primary tumours are usually squamous, treated mainly with radiotherapy (correct)
Correct. Primary vaginal cancer is rare, usually squamous, and managed with radiotherapy.
C. It is the commonest gynaecological cancer
It is among the rarest gynaecological cancers.
D. It is usually adenocarcinoma in elderly women
Adenocarcinoma is uncommon and linked to diethylstilbestrol exposure in the young.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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