Try it
OBG · Gynaecological oncology: pelvic exenteration
Sample itemA woman 18 months after chemoradiation for cervical cancer has a central pelvic recurrence involving the bladder and vagina, with no pelvic side wall involvement or distant metastases on PET-CT. Which surgery offers potential cure?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Pelvic exenteration
Pelvic exenteration removes the pelvic organs en bloc, anterior, posterior or total, and is the only curative option for isolated central recurrence after full-dose radiotherapy. Pelvic side wall involvement or distant spread contraindicates it. It requires urinary and faecal diversion and extensive counselling.
Option by option
A. Further radiotherapy to the same field
Repeating full-dose radiotherapy risks severe toxicity and rarely cures.
B. Palliative chemotherapy only
Palliation is for disease unsuitable for surgery.
C. Pelvic exenteration (correct)
Correct. Exenteration is the curative option for central recurrence in a previously irradiated field.
D. Simple hysterectomy
Simple hysterectomy cannot clear a tumour involving the bladder and vagina.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More OBG questions
- Antenatal careA woman's last menstrual period began on 10 January 2026. Using Naegele's rule, what is…
- Obstetric drugsCarboprost (15-methyl PGF2α) is contraindicated in which condition?
- Hypertensive disorders of pregnancyA primigravida at 34 weeks has a blood pressure of 150/100 mmHg on two occasions and 2+…
- Obstetric immunologyAn Rh-negative mother delivers an Rh-positive baby. When should anti-D immunoglobulin be…