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OBG · Gynaecological oncology: Latzko triad
Sample itemA 55-year-old postmenopausal woman has intermittent profuse watery vaginal discharge, colicky lower abdominal pain relieved after the discharge, and a palpable adnexal mass that shrinks afterwards. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Carcinoma of the fallopian tube (hydrops tubae profluens)
Latzko's triad of profuse watery discharge, colicky pain and an adnexal mass that decreases after discharge describes fallopian tube carcinoma, in which the tube intermittently drains accumulated fluid. It is uncommon and often diagnosed at surgery. Treatment is staging surgery and platinum-based chemotherapy as for ovarian cancer.
Option by option
A. Endometrial polyp
A polyp does not cause an adnexal mass.
B. Tubo-ovarian abscess
A tubo-ovarian abscess presents with fever and acute tenderness.
C. Cervical carcinoma
Cervical carcinoma presents with contact bleeding and an abnormal cervix.
D. Carcinoma of the fallopian tube (hydrops tubae profluens) (correct)
Correct. This triad is characteristic of tubal carcinoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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