Cornea: Khodadoust line: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Cornea: Khodadoust line

Sample item

Two months after a penetrating keratoplasty, a patient has a red eye with a linear line of keratic precipitates moving across the graft endothelium. This sign indicates:

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Endothelial graft rejection

Khodadoust line is a line of inflammatory cells on the graft endothelium that advances across the graft in endothelial rejection, the most serious type. It needs intense topical and sometimes systemic steroids. Epithelial rejection shows a raised linear epithelial rejection line instead.

Option by option

  • A. Endothelial graft rejection (correct)

    Correct. The Khodadoust line marks endothelial rejection.

  • B. Suture abscess

    A suture abscess is localised at a suture.

  • C. Graft infection by fungus

    A fungal infection would show an infiltrate with feathery edges.

  • D. Epithelial rejection only

    Epithelial rejection shows a different line on the epithelium.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is A, Endothelial graft rejection. Khodadoust line is a line of inflammatory cells on the graft endothelium that advances across the graft in endothelial rejection, the most serious type.

Why is "Suture abscess" not the answer?

A suture abscess is localised at a suture.

Why is "Graft infection by fungus" not the answer?

A fungal infection would show an infiltrate with feathery edges.

Why is "Epithelial rejection only" not the answer?

Epithelial rejection shows a different line on the epithelium.

What concept does this question test?

It tests Cornea: Khodadoust line in Ophthalmology. It needs intense topical and sometimes systemic steroids. Epithelial rejection shows a raised linear epithelial rejection line instead.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cornea: Khodadoust line?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.