Glaucoma: OHTS trial: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: OHTS trial

Sample item

In ocular hypertension, which trial showed that topical hypotensive treatment reduced the incidence of POAG by about half?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Ocular Hypertension Treatment Study

OHTS showed that treating ocular hypertensives lowered conversion to POAG from about 9.5 to 4.4 percent over 5 years. Predictors were age, higher IOP, thin CCT, larger cup disc ratio and pattern standard deviation. EMGT examined early manifest glaucoma.

Option by option

  • A. Advanced Glaucoma Intervention Study

    AGIS compared laser and surgery sequences in advanced disease.

  • B. Early Manifest Glaucoma Trial

    EMGT studied early manifest glaucoma.

  • C. Ocular Hypertension Treatment Study (correct)

    Correct. OHTS addressed ocular hypertension.

  • D. Collaborative Normal Tension Glaucoma Study

    CNTGS studied normal tension glaucoma.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Ocular Hypertension Treatment Study. OHTS showed that treating ocular hypertensives lowered conversion to POAG from about 9.

Why is "Advanced Glaucoma Intervention Study" not the answer?

AGIS compared laser and surgery sequences in advanced disease.

Why is "Early Manifest Glaucoma Trial" not the answer?

EMGT studied early manifest glaucoma.

Why is "Collaborative Normal Tension Glaucoma Study" not the answer?

CNTGS studied normal tension glaucoma.

What concept does this question test?

It tests Glaucoma: OHTS trial in Ophthalmology. 5 to 4.4 percent over 5 years. Predictors were age, higher IOP, thin CCT, larger cup disc ratio and pattern standard deviation. EMGT examined early manifest glaucoma.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: OHTS trial?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.