Glaucoma: dorzolamide: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: dorzolamide

Sample item

A glaucoma patient has a known severe sulfonamide allergy. Which topical agent should be avoided?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Dorzolamide

Dorzolamide and brinzolamide are topical carbonic anhydrase inhibitors that contain a sulfonamide moiety, so caution is needed in allergy. They reduce aqueous formation. Latanoprost, timolol and brimonidine do not contain sulfonamides.

Option by option

  • A. Timolol

    Timolol is a beta blocker.

  • B. Brimonidine

    Brimonidine is an alpha-2 agonist.

  • C. Latanoprost

    Latanoprost is a prostaglandin analogue.

  • D. Dorzolamide (correct)

    Correct. Dorzolamide is a sulfonamide derivative.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is D, Dorzolamide. Dorzolamide and brinzolamide are topical carbonic anhydrase inhibitors that contain a sulfonamide moiety, so caution is needed in allergy.

Why is "Timolol" not the answer?

Timolol is a beta blocker.

Why is "Brimonidine" not the answer?

Brimonidine is an alpha-2 agonist.

Why is "Latanoprost" not the answer?

Latanoprost is a prostaglandin analogue.

What concept does this question test?

It tests Glaucoma: dorzolamide in Ophthalmology. They reduce aqueous formation. Latanoprost, timolol and brimonidine do not contain sulfonamides.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: dorzolamide?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.