Glaucoma: netarsudil: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: netarsudil

Sample item

Which antiglaucoma drug acts by Rho kinase inhibition, increasing trabecular outflow and reducing episcleral venous pressure?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Netarsudil

Netarsudil inhibits Rho kinase and the norepinephrine transporter, and acts on the trabecular pathway. Conjunctival hyperaemia and corneal verticillata are common side effects. It also lowers episcleral venous pressure, which other topical classes do not.

Option by option

  • A. Brinzolamide

    Brinzolamide is a carbonic anhydrase inhibitor.

  • B. Bimatoprost

    Bimatoprost is a prostamide that increases uveoscleral outflow.

  • C. Netarsudil (correct)

    Correct. Netarsudil is a Rho kinase inhibitor.

  • D. Brimonidine

    Brimonidine is an alpha-2 agonist.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Netarsudil. Netarsudil inhibits Rho kinase and the norepinephrine transporter, and acts on the trabecular pathway.

Why is "Brinzolamide" not the answer?

Brinzolamide is a carbonic anhydrase inhibitor.

Why is "Bimatoprost" not the answer?

Bimatoprost is a prostamide that increases uveoscleral outflow.

Why is "Brimonidine" not the answer?

Brimonidine is an alpha-2 agonist.

What concept does this question test?

It tests Glaucoma: netarsudil in Ophthalmology. Conjunctival hyperaemia and corneal verticillata are common side effects. It also lowers episcleral venous pressure, which other topical classes do not.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: netarsudil?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.