Glaucoma: ICE syndrome: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: ICE syndrome

Sample item

A young woman has unilateral glaucoma, corneal oedema, and iris atrophy with corectopia and hammered silver endothelium. Which condition is this?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Iridocorneal endothelial syndrome (essential iris atrophy)

ICE syndrome is a unilateral disorder of young to middle-aged women with abnormal endothelium that spreads across the angle and iris. Variants are Chandler syndrome, Cogan-Reese syndrome and essential iris atrophy. Treatment is for glaucoma and corneal oedema.

Option by option

  • A. Fuchs heterochromic iridocyclitis

    Fuchs heterochromic iridocyclitis has KPs and cataract.

  • B. Axenfeld-Rieger syndrome

    Axenfeld-Rieger is bilateral and congenital.

  • C. Iridocorneal endothelial syndrome (essential iris atrophy) (correct)

    Correct. Unilateral features with a hammered silver endothelium are ICE.

  • D. Pigment dispersion syndrome

    Pigment dispersion occurs in young myopic men with Krukenberg spindle.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Iridocorneal endothelial syndrome (essential iris atrophy). ICE syndrome is a unilateral disorder of young to middle-aged women with abnormal endothelium that spreads across the angle and iris.

Why is "Fuchs heterochromic iridocyclitis" not the answer?

Fuchs heterochromic iridocyclitis has KPs and cataract.

Why is "Axenfeld-Rieger syndrome" not the answer?

Axenfeld-Rieger is bilateral and congenital.

Why is "Pigment dispersion syndrome" not the answer?

Pigment dispersion occurs in young myopic men with Krukenberg spindle.

What concept does this question test?

It tests Glaucoma: ICE syndrome in Ophthalmology. Variants are Chandler syndrome, Cogan-Reese syndrome and essential iris atrophy. Treatment is for glaucoma and corneal oedema.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: ICE syndrome?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.