Retina: treatment of type 1 ROP: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Retina: treatment of type 1 ROP

Sample item

A 32-week premature infant has zone I ROP with plus disease. What is the recommended management?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Prompt laser photocoagulation or intravitreal anti-VEGF

Type 1 ROP (zone I any stage with plus, zone I stage 3, or zone II stage 2 or 3 with plus) needs treatment within 72 hours as per ETROP. Laser ablation of the avascular retina is standard, and anti-VEGF (bevacizumab or ranibizumab) is an alternative, especially in zone I. Surgery is for later stages.

Option by option

  • A. Oxygen therapy

    Oxygen increases ROP risk.

  • B. Vitamin E only

    Vitamin E does not treat established ROP.

  • C. Observation for 6 months

    Waiting risks progression to detachment.

  • D. Prompt laser photocoagulation or intravitreal anti-VEGF (correct)

    Correct. Treat type 1 ROP promptly.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is D, Prompt laser photocoagulation or intravitreal anti-VEGF. Type 1 ROP (zone I any stage with plus, zone I stage 3, or zone II stage 2 or 3 with plus) needs treatment within 72 hours as per ETROP.

Why is "Oxygen therapy" not the answer?

Oxygen increases ROP risk.

Why is "Vitamin E only" not the answer?

Vitamin E does not treat established ROP.

Why is "Observation for 6 months" not the answer?

Waiting risks progression to detachment.

What concept does this question test?

It tests Retina: treatment of type 1 ROP in Ophthalmology. Laser ablation of the avascular retina is standard, and anti-VEGF (bevacizumab or ranibizumab) is an alternative, especially in zone I. Surgery is for later stages.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Retina: treatment of type 1 ROP?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.