Retina: fundus fluorescein angiography: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Retina: fundus fluorescein angiography

Sample item

In fundus fluorescein angiography, which finding in the late phase is typical of a classic choroidal neovascular membrane in wet AMD?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Well-defined early lacy hyperfluorescence with progressive leakage

FFA uses intravenous sodium fluorescein, which is imaged by blue light excitation. Classic CNV gives early well-demarcated lacy hyperfluorescence with leakage in the late phase. Smokestack leakage is typical of central serous chorioretinopathy.

Option by option

  • A. Early hypofluorescence only

    Hypofluorescence arises from blockage and does not define CNV.

  • B. Blocked fluorescence from drusen only

    Drusen cause window defects or staining, not CNV leakage.

  • C. Well-defined early lacy hyperfluorescence with progressive leakage (correct)

    Correct. Early lacy filling with progressive leakage describes classic CNV.

  • D. Smokestack leakage with no pooling

    Smokestack leakage is seen in central serous chorioretinopathy.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Well-defined early lacy hyperfluorescence with progressive leakage. FFA uses intravenous sodium fluorescein, which is imaged by blue light excitation.

Why is "Early hypofluorescence only" not the answer?

Hypofluorescence arises from blockage and does not define CNV.

Why is "Blocked fluorescence from drusen only" not the answer?

Drusen cause window defects or staining, not CNV leakage.

Why is "Smokestack leakage with no pooling" not the answer?

Smokestack leakage is seen in central serous chorioretinopathy.

What concept does this question test?

It tests Retina: fundus fluorescein angiography in Ophthalmology. Classic CNV gives early well-demarcated lacy hyperfluorescence with leakage in the late phase. Smokestack leakage is typical of central serous chorioretinopathy.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Retina: fundus fluorescein angiography?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.