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Psychiatry · Anxiety disorders: GAD pharmacotherapy
Sample itemFor long-term pharmacological treatment of generalised anxiety disorder, which is first-line?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. An SSRI or SNRI
SSRIs and SNRIs such as escitalopram, sertraline or venlafaxine are first-line for generalised anxiety disorder. Benzodiazepines are for short-term relief because of dependence and tolerance. Buspirone and pregabalin are alternatives.
Option by option
A. An antipsychotic
Antipsychotics are not first-line for anxiety.
B. A long-term benzodiazepine
Long-term benzodiazepines cause tolerance and dependence.
C. A barbiturate
Barbiturates are obsolete because of dependence and overdose risk.
D. An SSRI or SNRI (correct)
Correct. SSRIs and SNRIs are first-line for long-term use.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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