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Psychiatry · Anxiety disorders: organic mimics
Sample itemA 35-year-old woman has episodic palpitations, headache, sweating and severe hypertension during attacks. Which investigation helps exclude an organic mimic of panic?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Plasma or urinary metanephrines
Paroxysmal hypertension with headache, sweating and palpitations suggests phaeochromocytoma, which mimics panic attacks. Metanephrines confirm it. Thyrotoxicosis, hypoglycaemia, arrhythmias and substance effects are other mimics to consider.
Option by option
A. Plasma or urinary metanephrines (correct)
Correct. Metanephrines screen for phaeochromocytoma.
B. Blood alcohol level
Alcohol level does not explain paroxysmal hypertension.
C. Serum lithium level
Lithium level is irrelevant without lithium use.
D. Antinuclear antibody titre
ANA is used for autoimmune disease.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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