Oesophagus: Barrett oesophagus: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Oesophagus: Barrett oesophagus

Sample item

A 55-year-old man with long-standing reflux has biopsy showing columnar epithelium with goblet cells in the distal oesophagus. This condition predisposes to which cancer?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Adenocarcinoma of the oesophagus

Barrett oesophagus is intestinal metaplasia from chronic acid exposure, and it carries a risk of dysplasia and adenocarcinoma, so surveillance endoscopy is advised. Squamous carcinoma is linked to tobacco, alcohol and hot drinks.

Option by option

  • A. Lymphoma

    Lymphoma is not related to Barrett.

  • B. Leiomyosarcoma

    Leiomyosarcoma is rare and unrelated.

  • C. Adenocarcinoma of the oesophagus (correct)

    Correct. Metaplasia leads to adenocarcinoma.

  • D. Squamous cell carcinoma of the oesophagus

    Squamous carcinoma is associated with smoking and alcohol rather than reflux metaplasia.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More ENT questions

Questions about this ENT question

What is the answer to this ENT question?

The best answer is C, Adenocarcinoma of the oesophagus. Barrett oesophagus is intestinal metaplasia from chronic acid exposure, and it carries a risk of dysplasia and adenocarcinoma, so surveillance endoscopy is advised.

Why is "Lymphoma" not the answer?

Lymphoma is not related to Barrett.

Why is "Leiomyosarcoma" not the answer?

Leiomyosarcoma is rare and unrelated.

Why is "Squamous cell carcinoma of the oesophagus" not the answer?

Squamous carcinoma is associated with smoking and alcohol rather than reflux metaplasia.

What concept does this question test?

It tests Oesophagus: Barrett oesophagus in ENT. Squamous carcinoma is linked to tobacco, alcohol and hot drinks.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Oesophagus: Barrett oesophagus?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.