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ENT · Larynx: Kaposi sarcoma
Sample itemA 34-year-old man with advanced HIV infection has hoarseness and a violaceous, non-ulcerated supraglottic lesion on laryngoscopy, with similar purple plaques on the palate. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Kaposi sarcoma
Kaposi sarcoma, associated with human herpesvirus 8, causes violaceous mucosal lesions of the palate and supraglottis in AIDS. It is managed with antiretroviral therapy and, if required, chemotherapy or radiotherapy. Biopsy can bleed heavily.
Option by option
A. Laryngeal papilloma
Papillomas are pale, warty and associated with HPV 6 and 11.
B. Vocal fold cyst
A cyst is a smooth submucosal swelling on the cord.
C. Reinke oedema
Reinke oedema is polypoid swelling of the vocal fold in smokers.
D. Kaposi sarcoma (correct)
Correct. Purple vascular lesions in HIV suggest Kaposi sarcoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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