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Dermatology · Skin cancer
Sample itemWhat feature in a pigmented lesion raises concern for melanoma?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Asymmetry and color variation
The key Skin cancer principle supports Asymmetry and color variation; this answer most directly accounts for the clinical finding, investigation, or initial management described.
Option by option
A. Temporary blanching
Temporary blanching may apply in another setting but is not the best answer here.
B. Uniform stable appearance
Uniform stable appearance is not supported by the important skin cancer clue.
C. Asymmetry and color variation (correct)
Correct. Asymmetry and color variation is the best response to the defining feature given.
D. Fine scaling only
Fine scaling only does not explain the condition or address the appropriate priority.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.