Immunopathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Immunopathology

Sample item

What is an autoimmune mechanism in Graves disease?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Antibody stimulation of TSH receptor

The defining Immunopathology relationship supports Antibody stimulation of TSH receptor; it is the option that most directly explains the biochemical pathway or pathological process in the stem.

Option by option

  • A. Antibody destruction of acetylcholine receptor

    Antibody destruction of acetylcholine receptor does not match the stated immunopathology mechanism.

  • B. Immune complex in glomeruli only

    Immune complex in glomeruli only is relevant in a different context but is not supported here.

  • C. Antibody stimulation of TSH receptor (correct)

    Correct. Antibody stimulation of TSH receptor is the appropriate conclusion from the key feature.

  • D. T-cell attack on myelin

    T-cell attack on myelin does not account for the central finding in this item.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Antibody stimulation of TSH receptor. The defining Immunopathology relationship supports Antibody stimulation of TSH receptor; it is the option that most directly explains the biochemical pathway or pathological process in the stem.

Why is "Antibody destruction of acetylcholine receptor" not the answer?

Antibody destruction of acetylcholine receptor does not match the stated immunopathology mechanism.

Why is "Immune complex in glomeruli only" not the answer?

Immune complex in glomeruli only is relevant in a different context but is not supported here.

Why is "T-cell attack on myelin" not the answer?

T-cell attack on myelin does not account for the central finding in this item.

What concept does this question test?

It tests Immunopathology in Pathology. The correct option holds because: Correct. Antibody stimulation of TSH receptor is the appropriate conclusion from the key feature.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Immunopathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.