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General Medicine · Rheumatology
Sample itemWhat feature helps distinguish systemic lupus erythematosus from isolated mechanical pain?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Multisystem autoimmune features
The key Rheumatology principle supports Multisystem autoimmune features; this option most directly explains the clinical pattern, diagnostic priority, or initial management principle given in the stem.
Option by option
A. Normal rash-free state
Normal rash-free state has a different clinical context and is not the best answer here.
B. Pain only after exertion
Pain only after exertion does not match the stated rheumatology feature.
C. Multisystem autoimmune features (correct)
Correct. Multisystem autoimmune features is directly supported by the key information.
D. No laboratory abnormalities ever
No laboratory abnormalities ever does not address the diagnosis or priority described.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.