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Pathology · Inflammation
Sample itemWhich mediator causes vasodilation and increased vascular permeability early in inflammation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Histamine
The core Inflammation principle identifies Histamine as the best answer because it most directly explains the biochemical pathway or tissue response described in the stem.
Option by option
A. Erythropoietin
Erythropoietin does not account for the central finding in this sample.
B. Histamine (correct)
Correct. Histamine is supported by the key clue given.
C. Insulin
Insulin does not match the stated inflammation mechanism.
D. Thyroxine
Thyroxine is relevant in another context but is not the best answer here.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.