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Microbiology · Immunology
Sample itemWhat immunoglobulin predominates in mucosal secretions?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. IgA
Secretory IgA predominates in saliva, tears, breast milk, and mucosal secretions, where it helps neutralize pathogens without intense inflammation.
Option by option
A. IgM
IgM is prominent early in primary humoral responses.
B. IgE
IgE is associated with allergy and helminth responses.
C. IgG
IgG is the most abundant serum immunoglobulin.
D. IgA (correct)
Correct: IgA is the major mucosal-secretory immunoglobulin.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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