Immunology: practice question

A Microbiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Microbiology · Immunology

Sample item

What immunoglobulin is produced first in a primary humoral response?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. IgM

IgM is the first antibody class produced in a primary response before class switching generates other isotypes such as IgG or IgA.

Option by option

  • A. IgG

    IgG rises later and provides durable systemic immunity.

  • B. IgM (correct)

    Correct: IgM appears first in primary antibody response.

  • C. IgE

    IgE is associated with type I allergy and parasites.

  • D. IgA

    IgA is the dominant mucosal secretory antibody.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Microbiology questions

Questions about this Microbiology question

What is the answer to this Microbiology question?

The best answer is B, IgM. IgM is the first antibody class produced in a primary response before class switching generates other isotypes such as IgG or IgA.

Why is "IgG" not the answer?

IgG rises later and provides durable systemic immunity.

Why is "IgE" not the answer?

IgE is associated with type I allergy and parasites.

Why is "IgA" not the answer?

IgA is the dominant mucosal secretory antibody.

What concept does this question test?

It tests Immunology in Microbiology. The correct option holds because: Correct: IgM appears first in primary antibody response.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Immunology?

Make a one-line identity card for each organism: shape and stain, defining test, toxin, disease and drug. Then use the flashcards and the other Microbiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.