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Pharmacology · Pharmacodynamics
Sample itemWhat is the therapeutic index intended to reflect?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Relative safety margin
The therapeutic index compares toxic and effective dose ranges, providing a rough indication of a drug's safety margin under defined conditions.
Option by option
A. Rate of absorption
Absorption rate is a pharmacokinetic parameter.
B. Relative safety margin (correct)
Correct: therapeutic index estimates separation of toxic and effective doses.
C. Time to first dose
Time to first dose is an administration detail.
D. Drug taste
Taste does not define a drug safety margin.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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