Try it
Pharmacology · Analgesics
Sample itemWhat is a major adverse effect of long-term opioid use?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Constipation
Opioid activation of gut receptors decreases gastrointestinal motility and secretion, making constipation a frequent persistent adverse effect requiring prevention and review.
Option by option
A. Constipation (correct)
Correct: opioids commonly slow bowel motility and cause constipation.
B. Improved respiratory drive
Opioids can depress rather than improve respiratory drive.
C. Permanent pain cure
Opioids do not permanently cure pain.
D. Hyperalertness
Sedation is more typical than hyperalertness.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.