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Pharmacology · Analgesics
Sample itemWhat is a major risk of NSAID therapy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Gastrointestinal ulceration
NSAIDs inhibit prostaglandin synthesis, reducing protective gastric mucosal effects and potentially causing dyspepsia, ulceration, or gastrointestinal bleeding.
Option by option
A. Mydriasis
Mydriasis is not a typical NSAID effect.
B. Gastrointestinal ulceration (correct)
Correct: prostaglandin inhibition increases ulcer and bleed risk.
C. Improved renal perfusion
NSAIDs can reduce rather than improve renal perfusion.
D. Opioid withdrawal
Opioid withdrawal is unrelated to NSAID use.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.