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Dermatology · Skin cancer
Sample itemWhich feature in a pigmented lesion raises concern for melanoma?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Asymmetry and changing color
Asymmetry, border irregularity, color variation, evolution, and concerning diameter changes are warning features that should prompt melanoma assessment.
Option by option
A. Uniform stable shape
A uniform stable lesion is less concerning than an evolving asymmetric one.
B. Transient blanching
Transient blanching reflects vascular response, not melanoma criteria.
C. Asymmetry and changing color (correct)
Correct: asymmetry and evolving color are melanoma warning signs.
D. Fine scale only
Fine scale alone is nonspecific and not a principal melanoma warning sign.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.