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General Medicine · Rheumatology
Sample itemWhat polarized-light finding supports pseudogout?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Rhomboid positively birefringent crystals
Pseudogout results from calcium pyrophosphate deposition, which appears as rhomboid-shaped positively birefringent crystals in synovial fluid microscopy.
Option by option
A. Calcium oxalate crystals
Calcium oxalate crystals are not the characteristic pseudogout finding.
B. Cholesterol crystals
Cholesterol crystals do not define pseudogout.
C. Rhomboid positively birefringent crystals (correct)
Correct: calcium pyrophosphate crystals are rhomboid and positively birefringent.
D. Needle negatively birefringent crystals
Needle-shaped negatively birefringent crystals indicate gout.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.