Lipid metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Lipid metabolism

Sample item

What ketone body cannot be used as fuel by the liver?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Acetoacetate

The liver produces ketone bodies such as acetoacetate but cannot use them because it lacks thiophorase, the enzyme needed for ketone-body utilization.

Option by option

  • A. Palmitate

    Palmitate is a fatty acid that can undergo hepatic beta-oxidation.

  • B. Glucose

    Glucose can be used by liver for metabolism and storage.

  • C. Acetoacetate (correct)

    Correct: liver exports acetoacetate but cannot oxidize it without thiophorase.

  • D. Glycerol

    Glycerol can enter hepatic gluconeogenic pathways.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is C, Acetoacetate. The liver produces ketone bodies such as acetoacetate but cannot use them because it lacks thiophorase, the enzyme needed for ketone-body utilization.

Why is "Palmitate" not the answer?

Palmitate is a fatty acid that can undergo hepatic beta-oxidation.

Why is "Glucose" not the answer?

Glucose can be used by liver for metabolism and storage.

Why is "Glycerol" not the answer?

Glycerol can enter hepatic gluconeogenic pathways.

What concept does this question test?

It tests Lipid metabolism in Biochemistry. The correct option holds because: Correct: liver exports acetoacetate but cannot oxidize it without thiophorase.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Lipid metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.