Lipid metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Lipid metabolism

Sample item

What enzyme hydrolyzes triglycerides in chylomicrons at capillary endothelium?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Lipoprotein lipase

Lipoprotein lipase acts on triglycerides in circulating chylomicrons and VLDL, releasing fatty acids for uptake by muscle and adipose tissue.

Option by option

  • A. Lipoprotein lipase (correct)

    Correct: lipoprotein lipase clears triglyceride from chylomicrons and VLDL.

  • B. Hormone-sensitive lipase

    Hormone-sensitive lipase releases adipocyte stored fat.

  • C. Pancreatic lipase

    Pancreatic lipase digests dietary triglyceride in the intestinal lumen.

  • D. Phospholipase C

    Phospholipase C generates intracellular second messengers.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is A, Lipoprotein lipase. Lipoprotein lipase acts on triglycerides in circulating chylomicrons and VLDL, releasing fatty acids for uptake by muscle and adipose tissue.

Why is "Hormone-sensitive lipase" not the answer?

Hormone-sensitive lipase releases adipocyte stored fat.

Why is "Pancreatic lipase" not the answer?

Pancreatic lipase digests dietary triglyceride in the intestinal lumen.

Why is "Phospholipase C" not the answer?

Phospholipase C generates intracellular second messengers.

What concept does this question test?

It tests Lipid metabolism in Biochemistry. The correct option holds because: Correct: lipoprotein lipase clears triglyceride from chylomicrons and VLDL.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Lipid metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.