Renal physiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Renal physiology

Sample item

What substance is the ideal experimental marker of glomerular filtration rate?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Inulin

Inulin is freely filtered and neither reabsorbed nor secreted, so its clearance equals glomerular filtration rate in ideal experimental measurement.

Option by option

  • A. Inulin (correct)

    Correct: inulin clearance represents true GFR experimentally.

  • B. Creatinine

    Creatinine approximates GFR but is partly secreted.

  • C. Glucose

    Glucose is reabsorbed and cannot be used as a GFR marker.

  • D. Albumin

    Albumin is normally retained by the filtration barrier.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is A, Inulin. Inulin is freely filtered and neither reabsorbed nor secreted, so its clearance equals glomerular filtration rate in ideal experimental measurement.

Why is "Creatinine" not the answer?

Creatinine approximates GFR but is partly secreted.

Why is "Glucose" not the answer?

Glucose is reabsorbed and cannot be used as a GFR marker.

Why is "Albumin" not the answer?

Albumin is normally retained by the filtration barrier.

What concept does this question test?

It tests Renal physiology in Physiology. The correct option holds because: Correct: inulin clearance represents true GFR experimentally.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Renal physiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.