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Psychiatry · Psychopharmacology
Sample itemWhat blood test is required during clozapine therapy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Absolute neutrophil count
Clozapine can cause severe neutropenia or agranulocytosis, so regular absolute neutrophil-count monitoring is required under established safety programs.
Option by option
A. Serum amylase
Amylase does not monitor the key clozapine hematologic risk.
B. Absolute neutrophil count (correct)
Correct: ANC monitoring detects clozapine-related neutropenia.
C. Troponin only
Troponin may be used for specific concerns but not the routine core requirement.
D. Calcium only
Calcium alone does not identify agranulocytosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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