Pharmacokinetics: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Pharmacology · Pharmacokinetics

Sample item

What property determines the fraction of an oral dose reaching systemic circulation?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Bioavailability

Bioavailability is the fraction of an administered dose that reaches systemic circulation in unchanged form after absorption and first-pass metabolism.

Option by option

  • A. Bioavailability (correct)

    Correct: bioavailability measures systemic availability of administered dose.

  • B. Efficacy

    Efficacy is maximal achievable response.

  • C. Potency

    Potency is dose required for an effect.

  • D. Clearance

    Clearance measures drug removal from plasma over time.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, Bioavailability. Bioavailability is the fraction of an administered dose that reaches systemic circulation in unchanged form after absorption and first-pass metabolism.

Why is "Efficacy" not the answer?

Efficacy is maximal achievable response.

Why is "Potency" not the answer?

Potency is dose required for an effect.

Why is "Clearance" not the answer?

Clearance measures drug removal from plasma over time.

What concept does this question test?

It tests Pharmacokinetics in Pharmacology. The correct option holds because: Correct: bioavailability measures systemic availability of administered dose.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Pharmacokinetics?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.