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Pharmacology · Antihypertensives
Sample itemWhat electrolyte effect can occur with ACE inhibitors?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Hyperkalemia
ACE inhibitors reduce aldosterone signaling and can decrease renal potassium excretion, increasing the risk of hyperkalemia especially in renal impairment.
Option by option
A. Hypernatremia
Hypernatremia is not the usual consequence.
B. Hypercalcemia
Hypercalcemia is not the common ACE-inhibitor electrolyte effect.
C. Hypokalemia
Hypokalemia is more typical of potassium-wasting diuretics.
D. Hyperkalemia (correct)
Correct: reduced aldosterone can raise serum potassium.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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