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Pharmacology · Antihypertensives
Sample itemWhat adverse effect is common with dihydropyridine calcium-channel blockers?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Ankle edema
Dihydropyridine calcium-channel blockers dilate arterioles and can cause peripheral ankle edema from altered capillary hydrostatic pressure.
Option by option
A. Tendon rupture
Tendon rupture is associated with fluoroquinolone toxicity.
B. Ankle edema (correct)
Correct: arteriolar dilation commonly causes ankle edema.
C. Ototoxicity
Ototoxicity is associated with drugs such as aminoglycosides.
D. Dry cough
Dry cough is classically associated with ACE inhibitors.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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