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Pharmacology · Cardiovascular drugs
Sample itemWhat is the main antianginal effect of nitrates?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Reduce preload by venodilation
Nitrates predominantly dilate veins, lowering venous return and ventricular wall stress, which reduces myocardial oxygen demand in angina.
Option by option
A. Cause bronchoconstriction
Bronchoconstriction is not their therapeutic effect.
B. Reduce preload by venodilation (correct)
Correct: venodilation reduces preload and oxygen demand.
C. Increase platelet aggregation
Nitrates do not increase platelet aggregation.
D. Raise afterload
They tend to reduce rather than raise afterload at higher doses.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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