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Dermatology · Skin cancer
Sample itemWhat change in a pigmented lesion raises concern for melanoma?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Asymmetry and color variation
Melanoma warning features include asymmetry, irregular border, color variation, evolution, and concerning size, requiring timely skin examination.
Option by option
A. Uniform stable color
Uniform stable color is less concerning than change and variation.
B. Temporary blanching
Blanching reflects vascular response rather than melanoma criteria.
C. Asymmetry and color variation (correct)
Correct: asymmetry and varied color are melanoma warning signs.
D. Mild itch only
Mild itch alone is nonspecific.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.