Endocrinology: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

General Medicine · Endocrinology

Sample item

Which clinical combination most strongly suggests primary hypothyroidism?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Fatigue, cold intolerance, and constipation

Reduced thyroid hormone activity slows metabolic processes and commonly causes tiredness, cold intolerance, constipation, dry skin, and weight gain, although confirmation requires thyroid function testing.

Option by option

  • A. Tremor, heat intolerance, and weight loss

    Tremor and heat intolerance are more typical of thyrotoxicosis.

  • B. Polyuria, thirst, and fruity breath

    Fruity breath and polyuria suggest diabetic ketoacidosis.

  • C. Jaundice, pruritus, and pale stools

    This triad suggests obstructive cholestasis rather than thyroid disease.

  • D. Fatigue, cold intolerance, and constipation (correct)

    Correct: these symptoms fit reduced metabolic activity from hypothyroidism.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Medicine questions

Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is D, Fatigue, cold intolerance, and constipation. Reduced thyroid hormone activity slows metabolic processes and commonly causes tiredness, cold intolerance, constipation, dry skin, and weight gain, although confirmation requires thyroid function testing.

Why is "Tremor, heat intolerance, and weight loss" not the answer?

Tremor and heat intolerance are more typical of thyrotoxicosis.

Why is "Polyuria, thirst, and fruity breath" not the answer?

Fruity breath and polyuria suggest diabetic ketoacidosis.

Why is "Jaundice, pruritus, and pale stools" not the answer?

This triad suggests obstructive cholestasis rather than thyroid disease.

What concept does this question test?

It tests Endocrinology in General Medicine. The correct option holds because: Correct: these symptoms fit reduced metabolic activity from hypothyroidism.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Endocrinology?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.