Bioenergetics: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Bioenergetics

Sample item

Where is most ATP generated during aerobic cellular respiration?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Oxidative phosphorylation at the inner mitochondrial membrane

Oxidative phosphorylation couples electron transport to a proton gradient across the inner mitochondrial membrane, and ATP synthase uses that gradient to generate most ATP from aerobic glucose metabolism.

Option by option

  • A. Oxidative phosphorylation at the inner mitochondrial membrane (correct)

    Correct: the electron transport chain and ATP synthase generate most aerobic ATP.

  • B. Lysosomal degradation

    Lysosomes degrade cellular material and do not generate most ATP.

  • C. Cytosolic glycolysis alone

    Glycolysis produces a small amount of ATP in the cytosol.

  • D. The urea cycle

    The urea cycle consumes energy to dispose of nitrogen.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is A, Oxidative phosphorylation at the inner mitochondrial membrane. Oxidative phosphorylation couples electron transport to a proton gradient across the inner mitochondrial membrane, and ATP synthase uses that gradient to generate most ATP from aerobic glucose metabolism.

Why is "Lysosomal degradation" not the answer?

Lysosomes degrade cellular material and do not generate most ATP.

Why is "Cytosolic glycolysis alone" not the answer?

Glycolysis produces a small amount of ATP in the cytosol.

Why is "The urea cycle" not the answer?

The urea cycle consumes energy to dispose of nitrogen.

What concept does this question test?

It tests Bioenergetics in Biochemistry. The correct option holds because: Correct: the electron transport chain and ATP synthase generate most aerobic ATP.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Bioenergetics?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.