Necrosis: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Necrosis

Sample item

Which pattern of necrosis is expected in a cerebral infarct?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Liquefactive necrosis

Brain infarcts undergo liquefactive necrosis because enzymatic digestion of dead neural tissue predominates, eventually leaving a cystic space surrounded by reactive glial tissue.

Option by option

  • A. Fibrinoid necrosis

    Fibrinoid necrosis occurs in immune-mediated vascular injury.

  • B. Liquefactive necrosis (correct)

    Correct: ischemic brain tissue characteristically liquefies.

  • C. Gangrenous necrosis only

    Gangrene is a descriptive clinical term rather than the usual cerebral pattern.

  • D. Coagulative necrosis

    Coagulative necrosis is typical of infarction in most other solid organs.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is B, Liquefactive necrosis. Brain infarcts undergo liquefactive necrosis because enzymatic digestion of dead neural tissue predominates, eventually leaving a cystic space surrounded by reactive glial tissue.

Why is "Fibrinoid necrosis" not the answer?

Fibrinoid necrosis occurs in immune-mediated vascular injury.

Why is "Gangrenous necrosis only" not the answer?

Gangrene is a descriptive clinical term rather than the usual cerebral pattern.

Why is "Coagulative necrosis" not the answer?

Coagulative necrosis is typical of infarction in most other solid organs.

What concept does this question test?

It tests Necrosis in Pathology. The correct option holds because: Correct: ischemic brain tissue characteristically liquefies.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Necrosis?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.