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ENT · Otology
Sample itemWhich medication class is well known to have potential ototoxic effects at high doses or in susceptible patients?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Aminoglycoside antibiotics
Aminoglycosides can damage cochlear or vestibular hair cells, causing ototoxicity risk that depends on dose, duration, renal function, concurrent drugs, and individual susceptibility.
Option by option
A. Aminoglycoside antibiotics (correct)
Correct: aminoglycosides have recognized cochlear and vestibular toxicity risk.
B. Antacids
Simple antacids are not usually associated with ototoxicity.
C. Proton-pump inhibitors
Proton-pump inhibitors are not a classic ototoxic medication class.
D. Topical emollients
Topical emollients are not typical systemic ototoxins.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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