Drug receptors: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Drug receptors

Sample item

What is the usual effect of a competitive antagonist?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Raises apparent Km without lowering Emax

Competitive antagonists can be overcome by more agonist, shifting the dose-response curve right without reducing maximal effect.

Option by option

  • A. Increases drug absorption

    Absorption is not the receptor effect.

  • B. Raises apparent Km without lowering Emax (correct)

    Correct: more agonist can overcome competition.

  • C. Lowers Emax only

    Lower Emax suggests noncompetitive block.

  • D. Activates receptor fully

    Antagonists do not activate fully.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is B, Raises apparent Km without lowering Emax. Competitive antagonists can be overcome by more agonist, shifting the dose-response curve right without reducing maximal effect.

Why is "Increases drug absorption" not the answer?

Absorption is not the receptor effect.

Why is "Lowers Emax only" not the answer?

Lower Emax suggests noncompetitive block.

Why is "Activates receptor fully" not the answer?

Antagonists do not activate fully.

What concept does this question test?

It tests Drug receptors in Pharmacology. The correct option holds because: Correct: more agonist can overcome competition.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Drug receptors?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.