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Dermatology · Pigment disorders
Sample itemA patient develops sharply demarcated white patches because melanocytes are lost; which pigment disorder is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Acquired loss of skin pigmentation from melanocyte loss
Vitiligo is an acquired depigmenting disorder in which melanocytes are lost, producing sharply demarcated pale or white patches.
Option by option
A. A bruise caused by platelet loss
A bruise results from blood extravasation, not melanocyte loss.
B. A bacterial infection of hair follicles
Follicular bacterial infection is folliculitis.
C. A fungal infection of the nail
Nail fungus is onychomycosis.
D. Acquired loss of skin pigmentation from melanocyte loss (correct)
Correct: melanocyte loss causes depigmented patches.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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