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General Medicine · Haematology
Sample itemWhat is a major clinical concern in severe neutropenia with fever?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Occult serious infection requiring urgent treatment
Febrile neutropenia can represent rapidly progressive infection despite few local signs, so cultures and empiric treatment are urgently considered.
Option by option
A. Uncomplicated seasonal rhinitis
Rhinitis is usually less urgent in this setting.
B. Stable osteoarthritis
Stable osteoarthritis does not explain febrile neutropenia.
C. Occult serious infection requiring urgent treatment (correct)
Correct: neutropenia reduces the ability to contain infection.
D. Simple mechanical back pain
Mechanical pain is not the key life-threatening concern.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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